cpt 11 Search Results


irinotecan  (MedChemExpress)
95
MedChemExpress irinotecan

Irinotecan, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/Irinotecan/pmc11971274-19-0-8
Average 95 stars, based on 1 article reviews
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cpt 11  (TargetMol)
93
TargetMol cpt 11
The workflow of the study. The male ICR mice were treated <t>with</t> <t>CPT-11</t> (20 mg/kg daily; i.p.) to establish the IIM animal model. On the 9th day after administration, the serum, intestinal, colonic, hepatic, and splenic samples were collected. Gas chromatography–mass spectrometry (GC–MS) was used to investigate the metabolic alterations in the main tissues of the animal model. Multivariate statistical analyses, including GC–MS data processing, pattern recognition analysis, and pathway analysis, were performed.
Cpt 11, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/Irinotecan/pmc09520243-77-0-1
Average 93 stars, based on 1 article reviews
cpt 11 - by Bioz Stars, 2026-11
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cpt 11 irinotecan  (Tocris)
94
Tocris cpt 11 irinotecan
The workflow of the study. The male ICR mice were treated <t>with</t> <t>CPT-11</t> (20 mg/kg daily; i.p.) to establish the IIM animal model. On the 9th day after administration, the serum, intestinal, colonic, hepatic, and splenic samples were collected. Gas chromatography–mass spectrometry (GC–MS) was used to investigate the metabolic alterations in the main tissues of the animal model. Multivariate statistical analyses, including GC–MS data processing, pattern recognition analysis, and pathway analysis, were performed.
Cpt 11 Irinotecan, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/CPT+11/pm34494619-141-9-2
Average 94 stars, based on 1 article reviews
cpt 11 irinotecan - by Bioz Stars, 2026-11
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irinotecan  (Aladdin Scientific Corporation)
93
Aladdin Scientific Corporation irinotecan
MZCC characterization. ( A ) UV−Vis absorbance spectra of <t>ZIF-8,</t> <t>CPT-11,</t> CCM, ZIC and ZICC. ( B ) FT-IR of CCM, CPT-11, ZIF-8, ZIC and ZICC. ( C ) XRD of CCM, ZIF-8, ZIC, ZICC and MZCC. ( D ) TEM image of ZIC, ZICC and MZCC. Scale bar: 100 nm. ( E ) Dynamic light scattering of ZIC, ZICC and MZCC. ( F ) Zeta potentials of ZIC, ZICC and MZCC. ( G ) SDS-PAGE of marker, MCM, ZICC and MZCC.
Irinotecan, supplied by Aladdin Scientific Corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/Irinotecan/pmc12640645-35-0-4
Average 93 stars, based on 1 article reviews
irinotecan - by Bioz Stars, 2026-11
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irinotecan  (Tocris)
93
Tocris irinotecan
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Irinotecan, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/CPT+11/pm37894284-48-22-24
Average 93 stars, based on 1 article reviews
irinotecan - by Bioz Stars, 2026-11
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irinotecan hydrochloride  (TargetMol)
93
TargetMol irinotecan hydrochloride
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Irinotecan Hydrochloride, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/Irinotecan+Hydrochloride/pmc10798734-34-11-23
Average 93 stars, based on 1 article reviews
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biotin-11-cpt  (Enzo Biochem)
90
Enzo Biochem biotin-11-cpt
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Biotin 11 Cpt, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/biotin+11+cpt/pmc02708360-62-12-15
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irinotecan hydrochloride cpt-11 camptosar  (Pharmacia Upjohn LLC)
90
Pharmacia Upjohn LLC irinotecan hydrochloride cpt-11 camptosar
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Irinotecan Hydrochloride Cpt 11 Camptosar, supplied by Pharmacia Upjohn LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/cpt+11/10__1158_slash_0008___5472__can___04___2488-60-15-24
Average 90 stars, based on 1 article reviews
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cpt-11  (CH Instruments)
90
CH Instruments cpt-11
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Cpt 11, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/cpt+11/10__2147_slash_ott__s137644-65-12-18
Average 90 stars, based on 1 article reviews
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irinotecan (cpt11)  (NanoCarrier Co)
90
NanoCarrier Co irinotecan (cpt11)
Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = <t>Irinotecan,</t> 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).
Irinotecan (Cpt11), supplied by NanoCarrier Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cpt+11/cpt+11+nanocarrier/10__1158_slash_1078___0432__ccr___07___0780-11-1-14
Average 90 stars, based on 1 article reviews
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Image Search Results


Journal: Cell Death & Disease

Article Title: Mitochondrial, metabolic and bioenergetic adaptations drive plasticity of colorectal cancer cells and shape their chemosensitivity

doi: 10.1038/s41419-025-07596-y

Figure Lengend Snippet:

Article Snippet: Irinotecan , Blocks topoisomerase-1 , 2 μM , MedChemExpress , Cat. # HY- 16562.

Techniques: Concentration Assay

The workflow of the study. The male ICR mice were treated with CPT-11 (20 mg/kg daily; i.p.) to establish the IIM animal model. On the 9th day after administration, the serum, intestinal, colonic, hepatic, and splenic samples were collected. Gas chromatography–mass spectrometry (GC–MS) was used to investigate the metabolic alterations in the main tissues of the animal model. Multivariate statistical analyses, including GC–MS data processing, pattern recognition analysis, and pathway analysis, were performed.

Journal: Frontiers in Pharmacology

Article Title: Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

doi: 10.3389/fphar.2022.958882

Figure Lengend Snippet: The workflow of the study. The male ICR mice were treated with CPT-11 (20 mg/kg daily; i.p.) to establish the IIM animal model. On the 9th day after administration, the serum, intestinal, colonic, hepatic, and splenic samples were collected. Gas chromatography–mass spectrometry (GC–MS) was used to investigate the metabolic alterations in the main tissues of the animal model. Multivariate statistical analyses, including GC–MS data processing, pattern recognition analysis, and pathway analysis, were performed.

Article Snippet: CPT-11 (Target Mol) was dissolved in sodium chloride containing 5‰ dimethyl sulfoxide (DMSO; Tianjin Yongda Chemical Reagents, Tianjin, China) and prepared to the required concentrations.

Techniques: Animal Model, Gas Chromatography, Mass Spectrometry, Gas Chromatography-Mass Spectrometry

CPT-11 administration could lead to IIM in ICR mice. Mice were injected (i.p.) with CPT-11 (20 mg/kg, daily) for 9 days before being killed. (A) Body weight changes. (B) The DAI score. (C, D) Macroscopic images and length of the colon. (E) Histopathology score of colonic tissue. ( n = 7) ** p < 0.01, *** p < 0.001 vs. Control, t -test. (F) . Colonic tissues stained with H&E, and the photos were observed by confocal laser-scanning microscope, 50×, 200×, 400×.

Journal: Frontiers in Pharmacology

Article Title: Systematic evaluation of irinotecan-induced intestinal mucositis based on metabolomics analysis

doi: 10.3389/fphar.2022.958882

Figure Lengend Snippet: CPT-11 administration could lead to IIM in ICR mice. Mice were injected (i.p.) with CPT-11 (20 mg/kg, daily) for 9 days before being killed. (A) Body weight changes. (B) The DAI score. (C, D) Macroscopic images and length of the colon. (E) Histopathology score of colonic tissue. ( n = 7) ** p < 0.01, *** p < 0.001 vs. Control, t -test. (F) . Colonic tissues stained with H&E, and the photos were observed by confocal laser-scanning microscope, 50×, 200×, 400×.

Article Snippet: CPT-11 (Target Mol) was dissolved in sodium chloride containing 5‰ dimethyl sulfoxide (DMSO; Tianjin Yongda Chemical Reagents, Tianjin, China) and prepared to the required concentrations.

Techniques: Injection, Histopathology, Control, Staining, Laser-Scanning Microscopy

MZCC characterization. ( A ) UV−Vis absorbance spectra of ZIF-8, CPT-11, CCM, ZIC and ZICC. ( B ) FT-IR of CCM, CPT-11, ZIF-8, ZIC and ZICC. ( C ) XRD of CCM, ZIF-8, ZIC, ZICC and MZCC. ( D ) TEM image of ZIC, ZICC and MZCC. Scale bar: 100 nm. ( E ) Dynamic light scattering of ZIC, ZICC and MZCC. ( F ) Zeta potentials of ZIC, ZICC and MZCC. ( G ) SDS-PAGE of marker, MCM, ZICC and MZCC.

Journal: International Journal of Nanomedicine

Article Title: Engineered Cancer Cell Membrane-Functionalized Metal-Organic Frameworks for Irinotecan/Curcumin Codelivery in Colorectal Cancer: Enhanced Efficacy and Mitigated Toxicity

doi: 10.2147/IJN.S558675

Figure Lengend Snippet: MZCC characterization. ( A ) UV−Vis absorbance spectra of ZIF-8, CPT-11, CCM, ZIC and ZICC. ( B ) FT-IR of CCM, CPT-11, ZIF-8, ZIC and ZICC. ( C ) XRD of CCM, ZIF-8, ZIC, ZICC and MZCC. ( D ) TEM image of ZIC, ZICC and MZCC. Scale bar: 100 nm. ( E ) Dynamic light scattering of ZIC, ZICC and MZCC. ( F ) Zeta potentials of ZIC, ZICC and MZCC. ( G ) SDS-PAGE of marker, MCM, ZICC and MZCC.

Article Snippet: Irinotecan was purchased from Aladdin Scientific Co., Ltd. (Shanghai, China).

Techniques: SDS Page, Marker

Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = Irinotecan, 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).

Journal: Cancers

Article Title: Exploring the Tumor-Suppressing Potential of PSCA in Pancreatic Ductal Adenocarcinoma.

doi: 10.3390/cancers15204917

Figure Lengend Snippet: Figure 5. Additive anti-tumor effects of chemotherapeutic drugs and PSCA. CN = control, Irino = Irinotecan, 5-Flu = 5-Fluorouracil, and Oxa = Oxaliplatin. The single and double asterisks indicate p < 0.05 and 0.01, respectively. (A–C) Additive MTT-based anti-tumor effect of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, or Oxaliplatin in PANC1 PDAC cells (48 h). (D) Additive anti-tumor effects of 2 µg/mL PSCA recombinant proteins with 1 µM Irinotecan, 5-Fluorouracil, and Oxaliplatin in the scratch-based two-dimensional motility assay (24 h).

Article Snippet: Tumor cells were treated with 2 μg/mL of recombinant PSCA proteins (#MBS2012408; MyBioSource, San Diego, CA, USA), or chemotherapeutic agents, such as Irinotecan (#2688, Tocris Bioscience), 5-Fluorouracil (#3257, Tocris Bioscience), and Oxaliplatin (#2623, Tocris Bioscience).

Techniques: Control, Recombinant, Motility Assay